Improve risk factors for coronary heart disease associated with low rates of death from coronary heart disease

§ January 19th, 2012 § Filed under pharmacy Comments Off

In 1994, 8 % of patients with stable coronary artery disease were taking statins against 78 % in 2005. Improvements in the treatment of patients with heart failure in the community were involved in about 750 fewer deaths (10 %). In 1994, 29 % of patients were compared with 67 % in 2005. Improvements in the treatment of patients with AMI, which represents 8 % of all deaths prevented or delayed.‘Coronary heart disease remains the leading cause of death worldwide and generates a significant economic burden. Rates of coronary heart disease mortality has declined significantly over the last three decades. Identify the underlying factors associated with this decline is essential for future planning health policy, strategies and priorities for primary and secondary prevention, ‘write the authors.

The authors add that the increasing prevalence of diabetes and body mass index had an inverse relationship associated with higher mortality from coronary heart disease by 6 % and 2 % respectively.

Harindra C. Wijeysundera, MD, of Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada, and colleagues conducted a study to determine the association between coronary heart disease prevention and treatment strategies with the decline in coronary mortality in Ontario. The researchers analyzed the relative risk and quantified the relationship between coronary mortality and (1) evidence-based therapies in 8 distinct subpopulations coronary heart disease (acute myocardial infarction [IMA], acute coronary syndromes, secondary prevention post-myocardial myocardial infarction, chronic ischemic heart disease, hospital vs. community and primary prevention for hyperlipidemia or) and population trends (2) in 6 risk factors (smoking, diabetes mellitus, systolic blood pressure, plasma cholesterol, exercise, and) .

From 1994 to 2005 in Ontario, Canada, there was a decrease of 35 % mortality (CHD), with about half the reduction associated with improvements in traditional risk factors for coronary heart disease, as levels in total and systolic blood pressure, a study of the May 12 issue of JAMA.

The researchers found that between 1994 and 2005, the age-adjusted death rate in Ontario CHD decreased by 35 %, 191-125 deaths per 100,000 inhabitants, the translation of a 7585 fewer deaths from coronary heart disease in 2005. The decline was concentrated in older patients of 75-84 years. Changes in risk factors were associated with a 48 % decline in overall mortality (a reduction of CHD deaths estimated 3660), and new medical and surgical treatments have been associated with 43 % of the decline (3280 and estimate of the total deaths prevented or delayed).

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